ABSTRACT
Background:Hypertension is one of the most common worldwide diseases afflicting humans & is one of the leading causes of death and disability among adults all over the world. It remains the major risk factor for coronary, cerebral and peripheral vascular disease. Aim: To study the levels of sodium and potassium in serum in patients with Essential Hypertension and to correlate it with Blood pressure in case of newly detected Essential Hypertensives. Methods:Prospective comparative study in patients with 100 (50 cases +50 controls) patients with essential hypertension. All the patients were subjected to detailed history taking, careful physical examination and biochemical analysis to exclude secondary hypertension. Results: The results of the study, between cases and controls were statistically significant. The mean value of serum sodium was 146 ± 2.81 mmol/L in males and 148 ± 4.2 mmol/L in females. The mean and standard deviation of serum potassium among cases was 3.79 ±0.179 mmols/L while on control groups it was 4.25 ±0.22 mmol/L. Conclusion: The conclusions of the study are serum sodium was significantly more among hypertensives and it was independent of associated risk factors and gender.